United States securities and exchange commission logo February 27, 2023 Ying Huang, Ph.D. Chief Executive Officer Legend Biotech Corporation 2101 Cottontail Lane Somerset, NJ 08873 Re: Legend Biotech Corp Form 20-F for Fiscal Year Ended December 31, 2021 File No. 001-39307 Dear Ying Huang: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Mark Ballantyne